ea0026p27 | Adrenal cortex | ECE2011
Ardito A
, Al Ghuzian A
, Fassnacht M
, Daffara F
, Leboulleux S
, Wortmann S
, Zaggia B
, De Francia S
, Volante Marco
, Gonzaga Luigi
, Berruti Alfredo
, Allolio Bruno
, Baudin Eric
, Terzolo Massimo
We have demonstrated that adjuvant mitotane prolong recurrence free survival (RFS) in patients with radically resected ACC. Aim of the present study was to correlate mitotane levels with patient outcome in an adjuvant setting in 3 different referral centres in Europe. There were 120 patients (45 W, 75 M, median age 44 years, range 1676) radically resected for ACC who were treated adjuvantly with mitotane from 1996 to 2010. ACC was stage I in 10 cases, II in 73, III in 31...